Tıbbi Laboratuvar Teknikleri Programı / Medical Laboratory Tecniques Program
Recent Submissions
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Photodynamic augmentation of oncolytic virus therapy for central nervous system malignancies
(Cancer Letters, 2023)Oncolytic viruses (OVs) have emerged as a clinical therapeutic modality potentially effective for cancers that evade conventional therapies, including central nervous system malignancies. Rationally designed combinatorial ... -
Potential genotoxic and biological effects of 1,4 dioxane on different model organisms
(Current Opinion in Environmental Science & Health, 2023)A suspected human carcinogen, the compound 1,4-dioxane (DXN) has been commonly employed as a solvent in the production of various cleaning applications, cosmetics, dyes, varnishes, waxes, and detergents. Leaked from ... -
Drosophila as a robust model system for assessing autophagy: a review
(Toxics, 2023)Autophagy is the process through which a body breaks down and recycles its own cellular components, primarily inside lysosomes. It is a cellular response to starvation and stress, which plays decisive roles in various ... -
Genetik hastalıklarda tüm ekzom analiz sonuçları
(2022)Giriş: Tüm Ekzom Analizi (TEA) genetik hastalıkların tanısında yüksek düzeyde sağladığı bilgi sebebiyle son yıllarda klinisyenler tarafından tercih edilen testdir. Bu çalışmada amacımız, merkezimizin TEA sonuçlarını ... -
Hemoglobinopatilerde Covid19
(2. Azerbaycan Hematoloji Uzmanlar Kongresi, 2022) -
The importance of Microrna21 as biomarker in hepatocellular carcinoma
(Genetics & Molecular Medicine, 2022)Objective: Hepatocellular carcinoma (HCC) is the fifth most common cancer and the second leading cause of cancerrelated deaths worldwide.The diagnosis of HCC patients remains difficult, especially early in the development ... -
The miR125b as biomarkers in the early diagnosis of bladder cancer
(Genetics & Molecular Medicine, 2022)Objective: Bladder cancer (BCa) is the fifth most common cancer and the second most common urinary tract cancer in worldwide. BCa accounts for 3% of all cancers and is particularly common in developed countries. Material ... -
The importance of MicroRNA 29a as a biomarker in colon cancer
(Genetics & Molecular Medicine, 2022)Introduction: Colon cancer (CC) has become one of the most common diseases in recent years.The incidence of (CC) varies greatly worldwide, depending on lifestyle, environment, and genetic causes. Endoscopy is invasive ... -
The role of microRNAs as biomarker in pancreas cancer
(Japanese Journal Gastroeneterology Research, 2022)Objective: Pancreatic cancer (PC) is an aggressive cancer of the digestive tract Overall survival for patients with pancreatic cancer is poor mainly due to the lack of biomarkers that enable early diagnosis. Several studies ... -
The importance of MicroRNA 106b as a biomarker in gastric cancer
(Japanese Journal of Gastroenterol Research, 2022)Objective: Gastric cancer (GC) is the fourth most common malignant disease worldwide, and it is observed 2-3 times more frequently in men than in women. It is important to make an early diagnosis in GC, by using screening ... -
Use of MicroRNAs as biomarkers in the early diagnosis of prostate cancer
Introduction: Prostate cancer (PCa) is a common type of cancer in western countries and prominent cause of mortality in men. The aim of the study was to evaluate miRNAs as biomarkers in PCa in healthy individuals and ... -
Drosophila melanogaster as a dynamic in vivo model organism reveals the hidden effects of interactions between microplastic/nanoplastic and heavy metals
(Journal of Applied Toxicology, 2022)Plastic waste in different environments has been constantly transforming into microplastic/nanoplastic (MNPLs). As they may coexist with other contaminants, they may behave as vectors that transport various toxic trace ... -
Genotoxicity mechanism of food preservative propionic acid in the in vivo Drosophila model: gut damage, oxidative stress, cellular immune response and DNA damage
(Informa Healthcare, 2022)Propionic acid is a short-chain fatty acid that is the main fermentation product of the enteric microbiome. It is found naturally and added to foods as a preservative and evaluated by health authorities as safe for use in ... -
Novel insights into acute/chronic genotoxic impact of exposure to tungsten oxide nanoparticles on Drosophila melanogaster
(Journal of Nanoparticle Research, 2022)Tungsten oxide nanoparticles (WO3 NPs) have now been employed by various products including electronics, smart screens, gas-biosensors, water purifiers, disinfectants, and biomedical applications. Despite this wide-ranging ... -
Trimetilolpropan triakrilat’ın potansiyel toksik, genotoksik ve mutajenik etkilerinin drosophila melanogaster kullanılarak araştırılması
(Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi, 2022)Trimetilolpropan triakrilat (TMPTA), mürekkepler, plastikler, ahşap ve metal kaplamalar gibi farklı malzeme ve formüllerde yaygın olarak kullanılan bir kimyasaldır. Birçok alanda yaygın olarak kullanılmasına rağmen bu ... -
Protective effects of resveratrol against genotoxicity induced by nano and bulk hydroxyapatite in Drosophila melanogaster
(Journal of Toxicology and Environmental Health, 2022)Hydroxyapatite (HAp) is a naturally occurring calcium phosphate mineral predominantly used for its biocompatibility in a number of areas such as bone grafting, prosthesis coating in dentistry, and targeted drug delivery. ... -
Exposure to boron trioxide nanoparticles and ions cause oxidative stress, DNA damage, and phenotypic alterations in Drosophila melanogaster as an in vivo model
(Journal of Applied Toxicology, 2022)Boron trioxide nanoparticles (B2O3 NPs) have recently been widely used in a range of applications including electronic device technologies, acousto-optic apparatus fields, and as nanopowder for the production of special ... -
Interactions of ingested polystyrene microplastics with heavy metals (cadmium or silver) as environmental pollutants: a comprehensive in vivo study using drosophila melanogaster
(Biology, 2022)Living organisms are now constantly exposed to microplastics and nanoplastics (MNPLs), and besides their toxic potential, they can also act as carriers of various hazardous elements such as heavy metals. Therefore, this ... -
Hazard assessment of the effects of acute and chronic exposure to permethrin, copper hydroxide, acephate, and validamycin nanopesticides on the physiology of drosophila: novel insights into the cellular internalization and biological effects
(International Journal of Molecular Sciences, 2022)New insights into the interactions between nanopesticides and edible plants are required in order to elucidate their impacts on human health and agriculture. Nanopesticides include formulations consisting of organic/inorganic ... -
Drosophila: a promising model for evaluating the toxicity of environmental pollutants
(Karaelmas Fen ve Mühendislik Dergisi, 2022)Environmental contamination has now become a major global issue with adverse effects on our health and food security. Humans and animals are being exposed to debilitating levels of contamination on a daily basis. Across ...
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