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Drosophila melanogaster as a dynamic in vivo model organism reveals the hidden effects of interactions between microplastic/nanoplastic and heavy metals
(Journal of Applied Toxicology, 2022)
Plastic waste in different environments has been constantly transforming into microplastic/nanoplastic (MNPLs). As they may coexist with other contaminants, they may behave as vectors that transport various toxic trace ...
Genetik hastalıklarda tüm ekzom analiz sonuçları
(2022)
Giriş: Tüm Ekzom Analizi (TEA) genetik hastalıkların tanısında yüksek düzeyde sağladığı bilgi sebebiyle son yıllarda klinisyenler tarafından tercih edilen testdir. Bu çalışmada amacımız, merkezimizin TEA sonuçlarını ...
Warburg Cinotti sendromu: Ddr2 geninde De Novo
(2022)
Giriş: Warburg-Cinotti sendromu (WRCN), otozomal dominant olarak kalıtılan çok nadir bir hastalıktır. WRCN ilerleyici kornea neovaskülarizasyonu, keloid oluşumu, kronik cilt ülserleri, deri altı doku kaybı, parmaklarda ...
The importance of MicroRNA 106b as a biomarker in gastric cancer
(Japanese Journal of Gastroenterol Research, 2022)
Objective: Gastric cancer (GC) is the fourth most common malignant disease worldwide, and it is observed 2-3 times more frequently in men than in women. It is important to make an early diagnosis in GC, by using screening ...
Genotoxicity mechanism of food preservative propionic acid in the in vivo Drosophila model: gut damage, oxidative stress, cellular immune response and DNA damage
(Informa Healthcare, 2022)
Propionic acid is a short-chain fatty acid that is the main fermentation product of the enteric microbiome. It is found naturally and added to foods as a preservative and evaluated by health authorities as safe for use in ...
Arid1B geninde yeni bir anlamsız mutasyon : Coffin-Siris
(2022)
Giriş: Coffin-Siris sendromu (CSS) nadir görülen konjenital malformasyon sendromlarından biridir. Yenidoğan döneminde konjenital anomalilerin belirgin olmaması ve farkedilmemesine rağmen, CSS tanısında birçok özellik tarif ...
Hemoglobinopatilerde Covid19
(2. Azerbaycan Hematoloji Uzmanlar Kongresi, 2022)
Exposure to boron trioxide nanoparticles and ions cause oxidative stress, DNA damage, and phenotypic alterations in Drosophila melanogaster as an in vivo model
(Journal of Applied Toxicology, 2022)
Boron trioxide nanoparticles (B2O3 NPs) have recently been widely used in a range of applications including electronic device technologies, acousto-optic apparatus fields, and as nanopowder for the production of special ...
Nadir hastalıkların tanısında tüm genom analizi
(2022)
Giriş: Nadir hastalıklar, görülme sıklığı 1/2000’den az olan hastalıklar olarak tanımlanır. Nadir hastalıklar genellikle birden fazla sistemi etkileyen oldukça heterojen bir gruptur. Bunların yaklaşık %80’i genetik nedenlere ...
Interactions of ingested polystyrene microplastics with heavy metals (cadmium or silver) as environmental pollutants: a comprehensive in vivo study using drosophila melanogaster
(Biology, 2022)
Living organisms are now constantly exposed to microplastics and nanoplastics (MNPLs), and besides their toxic potential, they can also act as carriers of various hazardous elements such as heavy metals. Therefore, this ...