Ara
Toplam kayıt 21, listelenen: 1-10
Nadir hastalıkların tanısında tüm genom analizi
(2022)
Giriş: Nadir hastalıklar, görülme sıklığı 1/2000’den az olan hastalıklar olarak tanımlanır. Nadir hastalıklar genellikle birden fazla sistemi etkileyen oldukça heterojen bir gruptur. Bunların yaklaşık %80’i genetik nedenlere ...
Arid1B geninde yeni bir anlamsız mutasyon : Coffin-Siris
(2022)
Giriş: Coffin-Siris sendromu (CSS) nadir görülen konjenital malformasyon sendromlarından biridir. Yenidoğan döneminde konjenital anomalilerin belirgin olmaması ve farkedilmemesine rağmen, CSS tanısında birçok özellik tarif ...
Exposure to boron trioxide nanoparticles and ions cause oxidative stress, DNA damage, and phenotypic alterations in Drosophila melanogaster as an in vivo model
(Journal of Applied Toxicology, 2022)
Boron trioxide nanoparticles (B2O3 NPs) have recently been widely used in a range of applications including electronic device technologies, acousto-optic apparatus fields, and as nanopowder for the production of special ...
The importance of MicroRNA 106b as a biomarker in gastric cancer
(Japanese Journal of Gastroenterol Research, 2022)
Objective: Gastric cancer (GC) is the fourth most common malignant disease worldwide, and it is observed 2-3 times more frequently in men than in women. It is important to make an early diagnosis in GC, by using screening ...
Interactions of ingested polystyrene microplastics with heavy metals (cadmium or silver) as environmental pollutants: a comprehensive in vivo study using drosophila melanogaster
(Biology, 2022)
Living organisms are now constantly exposed to microplastics and nanoplastics (MNPLs), and besides their toxic potential, they can also act as carriers of various hazardous elements such as heavy metals. Therefore, this ...
In vivo effects of 1,4-dioxane on genotoxic parameters and behavioral alterations in Drosophila melanogaster
(Journal of Toxicology and Environmental Health, Part A, 2022)
1,4-Dioxane (DXN) is used as solvent in different consumer products including cosmetics, paints, surfactants, and waxes. In addition, DXN is released as an unwanted contaminating by-product as a result of some reactions ...
The importance of MicroRNA 29a as a biomarker in colon cancer
(Genetics & Molecular Medicine, 2022)
Introduction: Colon cancer (CC) has become one of the most common diseases in recent years.The incidence of
(CC) varies greatly worldwide, depending on lifestyle, environment, and genetic causes. Endoscopy is invasive ...
The role of microRNAs as biomarker in pancreas cancer
(Japanese Journal Gastroeneterology Research, 2022)
Objective: Pancreatic cancer (PC) is an aggressive cancer of the digestive tract Overall survival for patients with pancreatic cancer is poor mainly due to the lack of biomarkers that enable early diagnosis. Several studies ...
Hazard assessment of the effects of acute and chronic exposure to permethrin, copper hydroxide, acephate, and validamycin nanopesticides on the physiology of drosophila: novel insights into the cellular internalization and biological effects
(International Journal of Molecular Sciences, 2022)
New insights into the interactions between nanopesticides and edible plants are required in order to elucidate their impacts on human health and agriculture. Nanopesticides include formulations consisting of organic/inorganic ...
Genotoxicity mechanism of food preservative propionic acid in the in vivo Drosophila model: gut damage, oxidative stress, cellular immune response and DNA damage
(Informa Healthcare, 2022)
Propionic acid is a short-chain fatty acid that is the main fermentation product of the enteric microbiome. It is found naturally and added to foods as a preservative and evaluated by health authorities as safe for use in ...