Now showing items 1-10 of 16
Photodynamic augmentation of oncolytic virus therapy for central nervous system malignancies
(Cancer Letters, 2023)
Oncolytic viruses (OVs) have emerged as a clinical therapeutic modality potentially effective for cancers that evade conventional therapies, including central nervous system malignancies. Rationally designed combinatorial ...
Heavy metal accumulation and genotoxic effects in levant vole (Microtus guentheri) collected from contaminated areas due to mining activities
(Environmental Pollution, 2020)
Heavy metal contamination is a serious environmental problem commonly monitored in various organisms. Small wild rodents are ideal biological monitors to show the extent of environmental pollution.The aim of this study was ...
Drosophila melanogaster as a dynamic in vivo model organism reveals the hidden effects of interactions between microplastic/nanoplastic and heavy metals
(Journal of Applied Toxicology, 2022)
Plastic waste in different environments has been constantly transforming into microplastic/nanoplastic (MNPLs). As they may coexist with other contaminants, they may behave as vectors that transport various toxic trace ...
Genotoxicity mechanism of food preservative propionic acid in the in vivo Drosophila model: gut damage, oxidative stress, cellular immune response and DNA damage
(Informa Healthcare, 2022)
Propionic acid is a short-chain fatty acid that is the main fermentation product of the enteric microbiome. It is found naturally and added to foods as a preservative and evaluated by health authorities as safe for use in ...
Exposure to boron trioxide nanoparticles and ions cause oxidative stress, DNA damage, and phenotypic alterations in Drosophila melanogaster as an in vivo model
(Journal of Applied Toxicology, 2022)
Boron trioxide nanoparticles (B2O3 NPs) have recently been widely used in a range of applications including electronic device technologies, acousto-optic apparatus fields, and as nanopowder for the production of special ...
Interactions of ingested polystyrene microplastics with heavy metals (cadmium or silver) as environmental pollutants: a comprehensive in vivo study using drosophila melanogaster
Living organisms are now constantly exposed to microplastics and nanoplastics (MNPLs), and besides their toxic potential, they can also act as carriers of various hazardous elements such as heavy metals. Therefore, this ...
Assessing the genotoxic effects of d-glucose and sucrose in drosophila melanogaster
(5. International Marmara Sciences Congress (IMASCON 2020 AUTUMN), 2020)
Hazard assessment of the effects of acute and chronic exposure to permethrin, copper hydroxide, acephate, and validamycin nanopesticides on the physiology of drosophila: novel insights into the cellular internalization and biological effects
(International Journal of Molecular Sciences, 2022)
New insights into the interactions between nanopesticides and edible plants are required in order to elucidate their impacts on human health and agriculture. Nanopesticides include formulations consisting of organic/inorganic ...
In vivo effects of 1,4-dioxane on genotoxic parameters and behavioral alterations in Drosophila melanogaster
(Journal of Toxicology and Environmental Health, Part A, 2022)
1,4-Dioxane (DXN) is used as solvent in different consumer products including cosmetics, paints, surfactants, and waxes. In addition, DXN is released as an unwanted contaminating by-product as a result of some reactions ...
Novel insights into acute/chronic genotoxic impact of exposure to tungsten oxide nanoparticles on Drosophila melanogaster
(Journal of Nanoparticle Research, 2022)
Tungsten oxide nanoparticles (WO3 NPs) have now been employed by various products including electronics, smart screens, gas-biosensors, water purifiers, disinfectants, and biomedical applications. Despite this wide-ranging ...