Toplam kayıt 46, listelenen: 41-46
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Modeling gene regulation in liver hepatocellular carcinoma with random forests
(BioMed Research International, 2016)Liver hepatocellular carcinoma (HCC) remains a leading cause of cancer-related death. Poor understanding of the mechanisms underlying HCC prevents early detection and leads to high mortality. We developed a random forest ... -
Modeling the combined effect of RNA-binding proteins and microRNAs in post-transcriptional regulation
(Nucleic Acids Research, 2016)Recent studies show that RNA-binding proteins (RBPs) and microRNAs (miRNAs) function in coordination with each other to control post-transcriptional regulation (PTR). Despite this, the majority of research to date has ... -
JBASE: Joint Bayesian Analysis of Subphenotypes and Epistasis
(Bioinformatics, 2015)Motivation: Rapid advances in genotyping and genome-wide association studies have enabled the discovery of many new genotype–phenotype associations at the resolution of individual markers. However, these associations explain ... -
Target-independent prediction of drug synergies using only drug lipophilicity
(Journal of Chemical Information and Modeling, 2014)Physicochemical properties of compounds have been instrumental in selecting lead compounds with increased drug-likeness. However, the relationship between physicochemical properties of constituent drugs and the tendency ... -
RBPmotif: a web server for the discovery of sequence and structure preferences of RNA-binding proteins
(Nucleic acids research, 2013)RBPmotif web server (http://www.rnamotif.org) implements tools to identify binding preferences of RNA-binding proteins (RBPs). Given a set of sequences that are known to be bound and unbound by the RBP of interest, RBPmotif ... -
Multigene genetic programming for sediment transport modeling in sewers for conditions of non-deposition with a bed deposit
(Elsevier, 2018)It is known that construction of large sewers based on consideration of flow with non-deposition without a bed deposit is not economical. Sewer design based on consideration of flow with non-deposition with a bed deposit ...
