Akademik Arşiv / Institutional Repository: Recent submissions
Now showing items 2061-2080 of 2160
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A comprehensive database of high-throughput sequencing-based RNA secondary structure probing data (structure surfer)
(BMC Bioinformatics, 2016)Background: RNA molecules fold into complex three-dimensional shapes, guided by the pattern of hydrogen bonding between nucleotides. This pattern of base pairing, known as RNA secondary structure, is critical to their ... -
Chemogenomics and orthology‐based design of antibiotic combination therapies
(Molecular Systems Biology, 2016)Combination antibiotic therapies are being increasingly used in the clinic to enhance potency and counter drug resistance. However, the large search space of candidate drugs and dosage regimes makes the identification ... -
Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression
(Nature Communications, 2016)A hallmark of inflammatory diseases is the excessive recruitment and influx of monocytes to sites of tissue damage and their ensuing differentiation into macrophages. Numerous stimuli are known to induce transcriptional ... -
Modeling gene regulation in liver hepatocellular carcinoma with random forests
(BioMed Research International, 2016)Liver hepatocellular carcinoma (HCC) remains a leading cause of cancer-related death. Poor understanding of the mechanisms underlying HCC prevents early detection and leads to high mortality. We developed a random forest ... -
Modeling the combined effect of RNA-binding proteins and microRNAs in post-transcriptional regulation
(Nucleic Acids Research, 2016)Recent studies show that RNA-binding proteins (RBPs) and microRNAs (miRNAs) function in coordination with each other to control post-transcriptional regulation (PTR). Despite this, the majority of research to date has ... -
JBASE: Joint Bayesian Analysis of Subphenotypes and Epistasis
(Bioinformatics, 2015)Motivation: Rapid advances in genotyping and genome-wide association studies have enabled the discovery of many new genotype–phenotype associations at the resolution of individual markers. However, these associations explain ... -
Target-independent prediction of drug synergies using only drug lipophilicity
(Journal of Chemical Information and Modeling, 2014)Physicochemical properties of compounds have been instrumental in selecting lead compounds with increased drug-likeness. However, the relationship between physicochemical properties of constituent drugs and the tendency ... -
Turizm sektörü girişimcilerinin yatırım kararlarını etkileyen iç ve dış etkenlerin belirlenmesi
(International West Asia Congress of Tourism Research, 2018)Bu araştırmanın amacı, Antalya Bölgesi’ndeki turizm yatırımcılarının, yatırım yapma süreçlerinde yatırım kararlarını nasıl aldıkları, hangi içsel ve dışsal nedenlerle hareket ettiklerini belirlemektir. Bu amaç doğrultusunda, ... -
Corporate website content related to disability in the top 50 fortune firms in Turkey
(International Journal of Management Economics and Business, 2018)As a result of worldwide increased awareness in disability, organizations in Turkey are also assumed to reconsider their values, norms and behaviors accordingly. Considering the intention of maintaining legitimacy in ... -
Exploring the performance of hotels’ websites for guests with disabilities: a content analysis approach
(Business & Management Studies: An International Journal, 2018)The globally rising awareness about the social inclusion of individuals with disabilities also influences the tourism and hospitality industry in Turkey. This exploratory research focuses on the disability related content ... -
Konut çatı ve cephelerinde farklı fotovoltaik sistem uygulamalarının değerlendirilmesi
(Trakya Üniversitesi Mühendislik Bilimleri Dergisi, 2018)Photovoltaic systems developed for the purpose of obtaining electricity from sunlight are becoming increasingly widespread. In addition to its traditional functions, the building shell have equipped with a suitable plant ... -
A comparison of classrooms’ layout based on the requirements of preschool literacy
(ICONARP, 2019)Classroom design has claimed to be an important factor in supporting the pre-schoolers’ literacy development. While many studies had focused on improving the overall environment of the classrooms, few studies are established ... -
Climate change impacts on meteorological drought using SPI and SPEI: case study of Ankara, Turkey
(Hydrological Sciences Journal, 2019)Using regionally downscaled and adjusted outputs of three global climate models (GCMs), meteorological drought analysis was accomplished across Ankara, the capital city of Turkey. To this end, standardized precipitation ... -
Cr: Colquiriite Lasers: Current Status and Challenges for Further Progress
(Progress in Quantum Electronics, 2019)Cr: Colquiriite laser materials (Cr:LiCAF, Cr:LiSAF, Cr:LiSGaF) own broad absorption bands in the visible region that allow direct-diode pumping by well-developed low-cost red diodes. Moreover, they possess broad emission ... -
RBPmotif: a web server for the discovery of sequence and structure preferences of RNA-binding proteins
(Nucleic acids research, 2013)RBPmotif web server (http://www.rnamotif.org) implements tools to identify binding preferences of RNA-binding proteins (RBPs). Given a set of sequences that are known to be bound and unbound by the RBP of interest, RBPmotif ... -
The outsider inside: Turkey and the domino effect of Arab Nationalism in 1958
(I.B. Tauris and Bloomsbury, 2020) -
Definition of Turkey’s National Interests in the Early Cold War Era: Divergence and Convergence between DP and RPP in the 1950s
(Ankara Üniversitesi SBF Dergisi, 2019)National interest is a widely debated concept in the IR literature while analyzing foreign policies of states. This paper analyzes Turkey’s national interests in the 1950s and argues that they were hard to define commonly ... -
Turistlerin kalabalık algısının alışveriş davranışlarına etkisi
(Anadolu Üniversitesi20. Ulusal Turizm Kongresi, 2019)Bu çalışma, turistlerin alışveriş deneyimleri esnasında algıladıkları kalabalığın genel alışveriş memnuniyeti ve harcama miktarı üzerindeki etkisinin belirlenmesi amacıyla gerçekleştirilmiştir. Bu amaçla, Antalya’nın Kaleiçi ... -
Otel yöneticilerinin 2016 Türkiye turizm krizine ilişkin öngörüleri ve kriz yönetim uygulamaları
(Journal of Yasar University, 2019)2016 yılında Türkiye’de yaşanan turizm krizi özellikle Rusya pazarı odaklı hizmet sunan otel işletmelerini etkilemiş ve otel yöneticilerini krizden sağ kurtulmaya yönelik çözüm yolları aramaya itmiştir. Otel yöneticileri ... -
Impacts of operational management proficiency levels of hotels on operational and marketing related decisions in time of crisis
(Journal of Tourism and Management Research, 2018)In this study, it is firstly aimed to develop a Hotel Operation Management Proficiency Scale and then to search if there are any differences between the decisions of hotels related to marketing and operation in time of ...
