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Structure of conflict graphs in constraint alignment problems and algorithms
(Discrete Mathematics Theoretical Computer Science, 2019)
We consider the constrained graph alignment problem which has applications in biological network analysis. Given two input graphs G1 = (V1, E1), G2 = (V2, E2), two vertices u1, v1 of G1 paired respectively to two vertices ...
MEXCOwalk: mutual exclusion and coverage based random walk to identify cancer modules
(Bioinformatics, 2019)
Motivation: Genomic analyses from large cancer cohorts have revealed the mutational heterogeneity problem
which hinders the identification of driver genes based only on mutation profiles. One way to tackle this problem ...
MITF-MIR211 axis is a novel autophagy amplifier system during cellular stress
(Autophagy, 2019)
Macroautophagy (autophagy) is an evolutionarily conserved recycling and stress response mechanism. Active at basal levels in eukaryotes, autophagy is upregulated under stress providing cells with building blocks such as ...
RBPSponge: genome-wide identification of lncRNAs that sponge RBPs
(Bioinformatics, 2019)
Long non-coding RNAs (lncRNAs) can act as molecular sponge or decoys for an RNA-binding protein (RBP) through their RBP-binding sites, thereby modulating the expression of all target genes of the corresponding RBP of ...