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Target-independent prediction of drug synergies using only drug lipophilicity
(Journal of Chemical Information and Modeling, 2014)
Physicochemical properties of compounds have been instrumental in selecting lead compounds with increased drug-likeness. However, the relationship between physicochemical properties of constituent drugs and the tendency ...
Comparison of treatment effects of different maxillary protraction methods in skeletal class III patients
(Orthodontics & Craniofacial Research, 2020)
Objective: The aim of this study was to compare treatment outcomes with different maxillary protraction methods in patients with skeletal Class III malocclusion resulting from maxillary retrognathia. Setting and Sample ...
Estimations of giant dipole resonance parameters using artificial neural network
(Applied Radiation and Isotopes, 2021)
In this study; Giant Dipole Resonance (GDR) parameters of the spherical nucleus have been estimated by using artificial neural network (ANN) algorithms. The ANN training has been carried out with the Levenberg–Marquardt ...
Heavy metal accumulation and genotoxic effects in levant vole (Microtus guentheri) collected from contaminated areas due to mining activities
(Environmental Pollution, 2020)
Heavy metal contamination is a serious environmental problem commonly monitored in various organisms. Small wild rodents are ideal biological monitors to show the extent of environmental pollution.The aim of this study was ...
Multigene genetic programming for sediment transport modeling in sewers for conditions of non-deposition with a bed deposit
(Elsevier, 2018)
It is known that construction of large sewers based on consideration of flow with non-deposition without a bed deposit is not economical. Sewer design based on consideration of flow with non-deposition with a bed deposit ...
Predicting clinical outcomes in neuroblastoma with genomic data integration
(Biology Direct, 2018)
Background: Neuroblastoma is a heterogeneous disease with diverse clinical outcomes. Current risk group models require improvement as patients within the same risk group can still show variable prognosis. Recently collected ...
Comparison of three-dimensional soft-tissue evaluations between skeletal and pseudo-class III malocclusions
(Nature Research, 2020)
The aim of our study was to compare soft tissue measurements with 3D imaging methods in individuals with untreated skeletal and pseudo-Class III malocclusions. The study sample consisted of 75 patients (38 males, 37 females, ...
Lymphedema information and prevention practices of women after breast cancer surgery
(Florence Nightingale Journal of Nursing, 2020)
AIM: This study was carried out to determine women’s knowledge about lymphedema precautions and their practice status. The sample of this descriptive and correlationally designed study included 107 women who underwent ...
Mathematical model of the ventricular action potential and effects of isoproterenol-induced cardiac hypertrophy in rats
(European Biophysics Journal, 2020)
Mathematical action potential (AP) modeling is a well-established but still-developing area of research to better understand physiological and pathological processes. In particular, changes in AP mechanisms in the isoproterenol ...
Modeling gene regulation in liver hepatocellular carcinoma with random forests
(BioMed Research International, 2016)
Liver hepatocellular carcinoma (HCC) remains a leading cause of cancer-related death. Poor understanding of the mechanisms underlying HCC prevents early detection and leads to high mortality. We developed a random forest ...
