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RBPmotif: a web server for the discovery of sequence and structure preferences of RNA-binding proteins 

Kazan, Hilal; Morris, Quaid (Nucleic acids research, 2013)
RBPmotif web server (http://www.rnamotif.org) implements tools to identify binding preferences of RNA-binding proteins (RBPs). Given a set of sequences that are known to be bound and unbound by the RBP of interest, RBPmotif ...
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Heavy metal accumulation and genotoxic effects in levant vole (Microtus guentheri) collected from contaminated areas due to mining activities 

Turna Demir, Fatma; Yavuz, Mustafa (Environmental Pollution, 2020)
Heavy metal contamination is a serious environmental problem commonly monitored in various organisms. Small wild rodents are ideal biological monitors to show the extent of environmental pollution.The aim of this study was ...
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A translational repression complex in developing mammalian neural stem cells that regulates neuronal specification 

Zahr, Siraj K.; Yang, Guang; Kazan, Hilal; Borrett, Michael J.; Voronova, Anastassia; Kaplan, David R.; Miller, Freda D. (Neuron, 2018)
The mechanisms instructing genesis of neuronal sub-types from mammalian neural precursors are not well understood. To address this issue, we have characterized the transcriptional landscape of radial glial precursors (RPs) ...
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MEXCOwalk: mutual exclusion and coverage based random walk to identify cancer modules 

Ahmed, Rafsan; Baali, Ilyes; Erten, Cesim; Hoxha, Evis; Kazan, Hilal (Bioinformatics, 2019)
Motivation: Genomic analyses from large cancer cohorts have revealed the mutational heterogeneity problem which hinders the identification of driver genes based only on mutation profiles. One way to tackle this problem ...
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JBASE: Joint Bayesian Analysis of Subphenotypes and Epistasis 

Kazan, Hilal; Çolak, Recep; Kim, TaeHyung; Oh, Yoomi; Cruz, Miguel; Valladares Salgado, Adan; Peralta, Jesus; Escobedo, Jorge; Parra, Esteban J.; Kim, Philip M.; Goldenberg, Anna (Bioinformatics, 2015)
Motivation: Rapid advances in genotyping and genome-wide association studies have enabled the discovery of many new genotype–phenotype associations at the resolution of individual markers. However, these associations explain ...
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Comparison of treatment effects of different maxillary protraction methods in skeletal class III patients 

Büyükçavuş, Muhammed Hilmi; Kale, Burak; Aydemir, Buğra (Orthodontics & Craniofacial Research, 2020)
Objective: The aim of this study was to compare treatment outcomes with different maxillary protraction methods in patients with skeletal Class III malocclusion resulting from maxillary retrognathia. Setting and Sample ...
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Impaired exercise capacity in electrostatic polyester powder paint workers 

Sirayder, Ukbe; Inal-Ince, Deniz; Acik, Cihangir; Soyuer, Ferhan (Inhalation Toxicology, 2021)
Purpose: Limited number of studies investigated the effects of Electrostatic powder paints (EPP) on human health. We investigated the effects of EPP exposure on lung function, exercise capacity, and quality of life, and ...
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Photo-neutron cross-section calculations of 54,56Fe, 90,91,92,94Zr, 93Nb and 107Ag isotopes with newly obtained giant dipole resonance parameters 

Özdoğan, Hasan; Şekerci, Mert; Kaplan, Abdullah (Applied Radiation and Isotopes, 2020)
The knowledge of the interaction of photons with matter is of vital importance to investigate fundamental nu- clear physics problems. Giant dipole resonance (GDR) mechanism is dominant up to 30 MeV at photo-absorption ...
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Target-independent prediction of drug synergies using only drug lipophilicity 

Kazan, Hilal; Yılancıoğlu, Kaan; Weinstein, Zohar B.; Meydan, Cem; Akhmetov, Azat; Toprak, Işıl; Durmaz, Arda; Iossifov, Ivan; Roth, Frederick P.; Çokol, Murat (Journal of Chemical Information and Modeling, 2014)
Physicochemical properties of compounds have been instrumental in selecting lead compounds with increased drug-likeness. However, the relationship between physicochemical properties of constituent drugs and the tendency ...
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Mathematical model of the ventricular action potential and effects of isoproterenol-induced cardiac hypertrophy in rats 

Şengül Ayan, Sevgi; Sırcan, Ahmet K.; Abewa, Mohamedou; Kurt, Ahmet; Dalaman, Uğur; Yaraş, Nazmi (European Biophysics Journal, 2020)
Mathematical action potential (AP) modeling is a well-established but still-developing area of research to better understand physiological and pathological processes. In particular, changes in AP mechanisms in the isoproterenol ...
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AuthorKazan, Hilal (15)Demir, Eşref (7)Özdoğan, Hasan (6)Kaplan, Abdullah (4)Şekerci, Mert (4)Ak, Muhammet Fatih (3)Baali, Ilyes (3)HafezQorani, Saber (3)Şengül Ayan, Sevgi (3)Bruin, Ruben G. de (2)... View MoreSubjectDrosophila melanogaster (4)Meyve sineği (4)Risk değerlendirmesi (4)Artificial neural network (3)EXFOR (3)Risk assessment (3)TALYS 1.95 (3)Breast cancer (2)Cancer (2)Genotoxicity (2)... View MoreDate Issued2020 (17)2021 (9)2016 (6)2019 (6)2018 (4)2013 (2)2014 (1)2015 (1)Has File(s)Yes (30)No (16)

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