Modeling and analyzing Ca2+ channel dynamics during cardiac action potential
Şengül Ayan, Sevgi
Sırcan, Ahmet K.
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We have studied the cardiac action potential model which consists of 26 nonlinear first-order differential equations in a detailed manner computationally. Later, it has been discussed what is the role of the Ca2+ ion channel to the cardiac action potential by applying a mathematical measure called contribution analysis. Computational simulations are done to analyze the roles of Ca2+ gating variables and detailed analysis showed the changing dynamics of Ca2+ channel during a cardiac action potential.