Güncel Gönderiler: Scopus İndeksli Yayınlar Koleksiyonu

Toplam kayıt 137, listelenen: 101-120

    • Evaluation of the effects of building materials on human health and healthy material selection 

      Kokulu, Nil; Acun Özgünler, Seden (Gazi University Journal of Science, 2019)
      According to the studies, people spend 90% of their life indoors and the amount of the harmfull gases in the buildings is higher than outdoor city pollution. They can cause diseases such as cancer, asthma, allergic reactions ...

    • Surface characteristics of scots pine wood heated at high temperatures after weathering 

      Küçüktüvek, Mustafa; Baysal, Ergün; Türkoğlu, Türkay; Peker, Hüseyin; Gündüz, Ahmet; Toker, Hilmi (Wood Research, 2017)
      This study was conducted to investigate some surface properties of wood specimens of heat treated Scots pine (Pinus sylvestris L.) after weathering such as surface hardness, surface roughness, gloss, and color changes. ...

    • Surface characteristics of heated and varnished oriental beech after accelerated weathering 

      Türkoğlu, Türkay; Kabasakal, Yahya; Baysal, Ergün; Gündüz, Ahmet; Küçüktüvek, Mustafa; Bayraktar, Dursun Kemal; Toker, Hilmi; Peker, Hüseyin (Wood Research, 2017)
      This study was performed to investigate some surface characteristics such as surface hardness, surface roughness, and color changes of heated and varnished Oriental beec (Fagus orientalis Lipsky) after accelerated weathering. ...

    • The effect of natural weathering on change in the color of heat treated and varnished scots pine and oriental beech woods 

      Kart, Şaban; Baysal, Ergün; Türkoğlu, Türkay; Küçüktüvek, Mustafa; Peker, Hüseyin; Altay, Çağlar; Gündüz, Ahmet; Toker, Hilmi (Wood Research, 2018)
      This study was designed to investigate color changes of heat treated and varnished Scots pine (Pinus sylvestris L.) and Oriental beech (Fagus orientalis L.) after 3 months of weathering. Heat treatment of Oriental beech ...

    • Some surface characteristics of varnished thermowood after weathering 

      Kart, Şaban; Baysal, Ergün; Küçüktüvek, Mustafa; Türkoğlu, Türkay; Toker, Hilmi; Altay, Çağlar; Cibo, Cihan; Peker, Hüseyin (Wood Research, 2019)
      This study was designed to investigate some surface characteristics such as glossiness and surface roughness changes of varnished thermowood after six months of weathering. Thermal modification of Scots pine (Pinus sylvestris ...

    • MITF-MIR211 axis is a novel autophagy amplifier system during cellular stress 

      Öztürk, Deniz Gülfem; Koçak, Muhammed; Akçay, Arzu; Kınoğlu, Kubilay; Kara, Erdoğan; Büyük, Yalçın; Kazan, Hilal; Gözüaçık, Devrim (Autophagy, 2019)
      Macroautophagy (autophagy) is an evolutionarily conserved recycling and stress response mechanism. Active at basal levels in eukaryotes, autophagy is upregulated under stress providing cells with building blocks such as ...

    • RBPSponge: genome-wide identification of lncRNAs that sponge RBPs 

      HafezQorani, Saber; Houdjedj, Aissa; Arıcı, Mehmet; Said, Abdesselam; Kazan, Hilal (Bioinformatics, 2019)
      Long non-coding RNAs (lncRNAs) can act as molecular sponge or decoys for an RNA-binding protein (RBP) through their RBP-binding sites, thereby modulating the expression of all target genes of the corresponding RBP of ...

    • A translational repression complex in developing mammalian neural stem cells that regulates neuronal specification 

      Zahr, Siraj K.; Yang, Guang; Kazan, Hilal; Borrett, Michael J.; Voronova, Anastassia; Kaplan, David R.; Miller, Freda D. (Neuron, 2018)
      The mechanisms instructing genesis of neuronal sub-types from mammalian neural precursors are not well understood. To address this issue, we have characterized the transcriptional landscape of radial glial precursors (RPs) ...

    • Predicting clinical outcomes in neuroblastoma with genomic data integration 

      Baali, Ilyes; Acar, D. Alp Emre; Aderinwale, Tunde W.; HafezQorani, Saber; Kazan, Hilal (Biology Direct, 2018)
      Background: Neuroblastoma is a heterogeneous disease with diverse clinical outcomes. Current risk group models require improvement as patients within the same risk group can still show variable prognosis. Recently collected ...

    • Inferring RBP-mediated regulation in lung squamous cell carcinoma 

      Lafzi, Atefeh; Kazan, Hilal (Plos One, 2016)
      RNA-binding proteins (RBPs) play key roles in post-transcriptional regulation of mRNAs. Dysregulations in RBP-mediated mechanisms have been found to be associated with many steps of cancer initiation and progression. Despite ...

    • A comprehensive database of high-throughput sequencing-based RNA secondary structure probing data (structure surfer) 

      Berkowitz, Nathan D.; Silverman, Ian M.; Childress, Daniel M.; Kazan, Hilal; Wang, Li-San; Gregory, Brian D. (BMC Bioinformatics, 2016)
      Background: RNA molecules fold into complex three-dimensional shapes, guided by the pattern of hydrogen bonding between nucleotides. This pattern of base pairing, known as RNA secondary structure, is critical to their ...

    • Chemogenomics and orthology‐based design of antibiotic combination therapies 

      Chandrasekaran, Sriram; Çokol-Çakmak, Melike; Şahin, Nil; Yılancıoğlu, Kaan; Kazan, Hilal; Collins, James J.; Çokol, Murat (Molecular Systems Biology, 2016)
      Combination antibiotic therapies are being increasingly used in the clinic to enhance potency and counter drug resistance. However, the large search space of candidate drugs and dosage regimes makes the identification ...

    • Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression 

      Bruin, Ruben G. de; Shiue, Lily; Prins, Jurrien; Boer, Hetty C. de; Singh, Anjana; Fagg, W. Samuel; Gils, Janine M. vans; Duijs, Jacques M. G. J.; Katzman, Sol; Kraaijeveld, Adriaan O.; Bohringer, Stefan; Leung, Wai Y.; Kielbasa, Szymon M.; Donahue, John P.; Zande, Patrick H. J. van der; Sijbom, Rick; Alem, Carla M. A. van; Bot, Ilze; Kooten, Cees van; Jukema, J. Wouter; Van Esch, Hilde; Rabelink, Ton J.; Kazan, Hilal; Biessen, Erik A. L.; Ares, Manuel; Zonneveld, Anton Jan van; Veer, Eric P. van der (Nature Communications, 2016)
      A hallmark of inflammatory diseases is the excessive recruitment and influx of monocytes to sites of tissue damage and their ensuing differentiation into macrophages. Numerous stimuli are known to induce transcriptional ...

    • Modeling gene regulation in liver hepatocellular carcinoma with random forests 

      Kazan, Hilal (BioMed Research International, 2016)
      Liver hepatocellular carcinoma (HCC) remains a leading cause of cancer-related death. Poor understanding of the mechanisms underlying HCC prevents early detection and leads to high mortality. We developed a random forest ...

    • Modeling the combined effect of RNA-binding proteins and microRNAs in post-transcriptional regulation 

      HafezQorani, Saber; Lafzi, Atefeh; Bruin, Ruben G. de; Zonneveld, Anton Jan van; Veer, Eric P. van der; Aydın Son, Yeşim; Kazan, Hilal (Nucleic Acids Research, 2016)
      Recent studies show that RNA-binding proteins (RBPs) and microRNAs (miRNAs) function in coordination with each other to control post-transcriptional regulation (PTR). Despite this, the majority of research to date has ...

    • Target-independent prediction of drug synergies using only drug lipophilicity 

      Kazan, Hilal; Yılancıoğlu, Kaan; Weinstein, Zohar B.; Meydan, Cem; Akhmetov, Azat; Toprak, Işıl; Durmaz, Arda; Iossifov, Ivan; Roth, Frederick P.; Çokol, Murat (Journal of Chemical Information and Modeling, 2014)
      Physicochemical properties of compounds have been instrumental in selecting lead compounds with increased drug-likeness. However, the relationship between physicochemical properties of constituent drugs and the tendency ...

    • Climate change impacts on meteorological drought using SPI and SPEI: case study of Ankara, Turkey 

      Danandeh Mehr, Ali; Sorman, Ali Ünal; Kahya, Ercan; Hesami Afshar, Mahdi (Hydrological Sciences Journal, 2019)
      Using regionally downscaled and adjusted outputs of three global climate models (GCMs), meteorological drought analysis was accomplished across Ankara, the capital city of Turkey. To this end, standardized precipitation ...

    • Cr: Colquiriite Lasers: Current Status and Challenges for Further Progress 

      Demirbaş, Ümit (Progress in Quantum Electronics, 2019)
      Cr: Colquiriite laser materials (Cr:LiCAF, Cr:LiSAF, Cr:LiSGaF) own broad absorption bands in the visible region that allow direct-diode pumping by well-developed low-cost red diodes. Moreover, they possess broad emission ...

    • RBPmotif: a web server for the discovery of sequence and structure preferences of RNA-binding proteins 

      Kazan, Hilal; Morris, Quaid (Nucleic acids research, 2013)
      RBPmotif web server (http://www.rnamotif.org) implements tools to identify binding preferences of RNA-binding proteins (RBPs). Given a set of sequences that are known to be bound and unbound by the RBP of interest, RBPmotif ...

    • Conflict management styles of professional tour guides: a cluster analysis 

      Caber, Meltem; Ünal, Caner; Dursun Cengizci, Aslıhan; Güven, Aylin (Tourism Management Perspectives, 2019)
      Professional tour guides play an important role in tourist satisfaction and the business success of tour agencies/operators, since they are directly in contact with tourists and are responsible for managing the tours. ...