Tıbbi Laboratuvar Teknikleri Programı / Medical Laboratory Tecniques Program
Recent Submissions
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Drosophila melanogaster as a dynamic in vivo model organism reveals the hidden effects of interactions between microplastic/nanoplastic and heavy metals
(Journal of Applied Toxicology, 2022)Plastic waste in different environments has been constantly transforming into microplastic/nanoplastic (MNPLs). As they may coexist with other contaminants, they may behave as vectors that transport various toxic trace ... -
Genotoxicity mechanism of food preservative propionic acid in the in vivo Drosophila model: gut damage, oxidative stress, cellular immune response and DNA damage
(Informa Healthcare, 2022)Propionic acid is a short-chain fatty acid that is the main fermentation product of the enteric microbiome. It is found naturally and added to foods as a preservative and evaluated by health authorities as safe for use in ... -
Novel insights into acute/chronic genotoxic impact of exposure to tungsten oxide nanoparticles on Drosophila melanogaster
(Journal of Nanoparticle Research, 2022)Tungsten oxide nanoparticles (WO3 NPs) have now been employed by various products including electronics, smart screens, gas-biosensors, water purifiers, disinfectants, and biomedical applications. Despite this wide-ranging ... -
Trimetilolpropan triakrilat’ın potansiyel toksik, genotoksik ve mutajenik etkilerinin drosophila melanogaster kullanılarak araştırılması
(Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi, 2022)Trimetilolpropan triakrilat (TMPTA), mürekkepler, plastikler, ahşap ve metal kaplamalar gibi farklı malzeme ve formüllerde yaygın olarak kullanılan bir kimyasaldır. Birçok alanda yaygın olarak kullanılmasına rağmen bu ... -
Protective effects of resveratrol against genotoxicity induced by nano and bulk hydroxyapatite in Drosophila melanogaster
(Journal of Toxicology and Environmental Health, 2022)Hydroxyapatite (HAp) is a naturally occurring calcium phosphate mineral predominantly used for its biocompatibility in a number of areas such as bone grafting, prosthesis coating in dentistry, and targeted drug delivery. ... -
Exposure to boron trioxide nanoparticles and ions cause oxidative stress, DNA damage, and phenotypic alterations in Drosophila melanogaster as an in vivo model
(Journal of Applied Toxicology, 2022)Boron trioxide nanoparticles (B2O3 NPs) have recently been widely used in a range of applications including electronic device technologies, acousto-optic apparatus fields, and as nanopowder for the production of special ... -
Interactions of ingested polystyrene microplastics with heavy metals (cadmium or silver) as environmental pollutants: a comprehensive in vivo study using drosophila melanogaster
(Biology, 2022)Living organisms are now constantly exposed to microplastics and nanoplastics (MNPLs), and besides their toxic potential, they can also act as carriers of various hazardous elements such as heavy metals. Therefore, this ... -
Hazard assessment of the effects of acute and chronic exposure to permethrin, copper hydroxide, acephate, and validamycin nanopesticides on the physiology of drosophila: novel insights into the cellular internalization and biological effects
(International Journal of Molecular Sciences, 2022)New insights into the interactions between nanopesticides and edible plants are required in order to elucidate their impacts on human health and agriculture. Nanopesticides include formulations consisting of organic/inorganic ... -
Drosophila: a promising model for evaluating the toxicity of environmental pollutants
(Karaelmas Fen ve Mühendislik Dergisi, 2022)Environmental contamination has now become a major global issue with adverse effects on our health and food security. Humans and animals are being exposed to debilitating levels of contamination on a daily basis. Across ... -
In vivo effects of 1,4-dioxane on genotoxic parameters and behavioral alterations in Drosophila melanogaster
(Journal of Toxicology and Environmental Health, Part A, 2022)1,4-Dioxane (DXN) is used as solvent in different consumer products including cosmetics, paints, surfactants, and waxes. In addition, DXN is released as an unwanted contaminating by-product as a result of some reactions ... -
Drosophila as a suitable in vivo model in the safety assessment of nanomaterials
(Springer Cham, 2022)Nanotechnology is often praised as the future technology that will revolutionize the world as we know it, because nanomaterials (NMs) offer numerous practical applications for a wide range of fields such as medicine, ... -
Mechanisms and biological impacts of graphene and multi-walled carbon nanotubes on Drosophila melanogaster: Oxidative stress, genotoxic damage, phenotypic variations, locomotor behavior, parasitoid resistance, and cellular immune response
(Journal Of Applied Toxicology, 2021)The use of graphene and multi-walled carbon nanotubes (MWCNTs) has now become rather common in medical applications as well as several other areas thanks to their useful physicochemical properties. While in vitro testing ... -
Toxicity mechanisms of nanoparticles in the male reproductive system
(Drug Metabolism Reviews, 2021)The field of nanotechnology has allowed for increasing nanoparticle (NP) exposure to the male reproductive system. Certain NPs have been reported to have adverse consequences on male germ and somatic cells. Germ cells are ... -
Bupleurum lycaonicum snogerup bitki türünün DNA üzerine etkisi
(2021)Özet Amaç Apiaceae familyası üyeleri, dünyada ekonomik öneme sahip bitki gruplarındandır. Bu çalışmada, Apiaceae familyasına ait çiçekli endemik bitki türü olan Bupleurum lycaonicum, bitki özütlerinin DNA üzerine etkisinin ... -
The potential use of drosophila as an in vivo model organism for COVID-19-related research: a review
(Turkish Journal of Biology, 2021)The world urgently needs effective antiviral approaches against emerging viruses, as shown by the coronavirus disease 2019 (COVID-19) pandemic, which has become an exponentially growing health crisis. Scientists from ... -
A comprehensive in vivo study using drosophila melanogaster: new insights into mechanisms and biological effects of permethrin nanopesticides
(The 6th ed. of the International Conference Nanotech France 2021, 2021) -
A systematic in vivo study of copper hydroxide nanopesticides using Drosophila melanogaster: Cellular uptake and biological impacts
(11th Congress of Toxicology in Developing Countries (CTDC11), 2021) -
Adverse biological effects of ingested polystyrene microplastics using Drosophila melanogaster as a model in vivo organism
(Journal of Toxicology and Environmental Health, Part A: Current Issues, 2021)The abundant presence and extensive use of polystyrene microplastics (PSMPs) has recently become a serious environmental concern, as impact of exposure to these substances on human health remains unknown. While in vitro ... -
The effect of teaching mitosis and meiosis subjects with computer-aided teaching materials on academic success
(3rd International Conference on Education, Technology and Science, 2020)In this study, the effect of teaching mitosis and meiosis subjects using computeraided teaching materials on academic success was investigated. The mixed method, which combines quantitative and qualitative research methods, ... -
Assessing the genotoxic effects of d-glucose and sucrose in drosophila melanogaster
(5. International Marmara Sciences Congress (IMASCON 2020 AUTUMN), 2020)
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