Ara
Toplam kayıt 26, listelenen: 11-20
RBPmotif: a web server for the discovery of sequence and structure preferences of RNA-binding proteins
(Nucleic acids research, 2013)
RBPmotif web server (http://www.rnamotif.org) implements tools to identify binding preferences of RNA-binding proteins (RBPs). Given a set of sequences that are known to be bound and unbound by the RBP of interest, RBPmotif ...
Predicting clinical outcomes in neuroblastoma with genomic data integration
(Biology Direct, 2018)
Background: Neuroblastoma is a heterogeneous disease with diverse clinical outcomes. Current risk group models require improvement as patients within the same risk group can still show variable prognosis. Recently collected ...
MITF-MIR211 axis is a novel autophagy amplifier system during cellular stress
(Autophagy, 2019)
Macroautophagy (autophagy) is an evolutionarily conserved recycling and stress response mechanism. Active at basal levels in eukaryotes, autophagy is upregulated under stress providing cells with building blocks such as ...
Identification and prioritization of personalized cancer drivers
(German Conference on Bioinformatics, 2022)
RBPSponge: genome-wide identification of lncRNAs that sponge RBPs
(Bioinformatics, 2019)
Long non-coding RNAs (lncRNAs) can act as molecular sponge or decoys for an RNA-binding protein (RBP) through their RBP-binding sites, thereby modulating the expression of all target genes of the corresponding RBP of ...
The P-body protein 4E-T represses translation to regulate the balance between cell genesis and establishment of the postnatal NSC pool
(Elsevier, 2023)
Here, we ask how developing precursors maintain the balance between cell genesis for tissue growth and establishment of adult stem cell pools, focusing on postnatal forebrain neural precursor cells (NPCs). We show that ...
Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression
(Nature Communications, 2016)
A hallmark of inflammatory diseases is the excessive recruitment and influx of monocytes to sites of tissue damage and their ensuing differentiation into macrophages. Numerous stimuli are known to induce transcriptional ...
A comprehensive database of high-throughput sequencing-based RNA secondary structure probing data (structure surfer)
(BMC Bioinformatics, 2016)
Background: RNA molecules fold into complex three-dimensional shapes, guided by the pattern of hydrogen bonding between nucleotides. This pattern of base pairing, known as RNA secondary structure, is critical to their ...
SCITUNA: a network alignment approach for integrating multiple single-cell RNA-Seq datasets
(15th International Symposium on Health Informatics and Bioinformatics, 2022)
The throughput and cost of single-cell RNA sequencing (scRNA-seq) are in continuous improvement, and so is the demand for larger-scale scRNA-seq data, which could require integrating multiple datasets from different ...
Community assessment of the predictability of cancer protein and phosphoprotein levels from genomics and transcriptomics
(Cell Systems, 2020)
Cancer is driven by genomic alterations, but the processes causing this disease are largely performed by proteins. However, proteins are harder and more expensive to measure than genes and transcripts. To catalyze developments ...