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MEXCOwalk: mutual exclusion and coverage based random walk to identify cancer modules
(Bioinformatics, 2019)
Motivation: Genomic analyses from large cancer cohorts have revealed the mutational heterogeneity problem
which hinders the identification of driver genes based only on mutation profiles. One way to tackle this problem ...
MITF-MIR211 axis is a novel autophagy amplifier system during cellular stress
(Autophagy, 2019)
Macroautophagy (autophagy) is an evolutionarily conserved recycling and stress response mechanism. Active at basal levels in eukaryotes, autophagy is upregulated under stress providing cells with building blocks such as ...
RBPSponge: genome-wide identification of lncRNAs that sponge RBPs
(Bioinformatics, 2019)
Long non-coding RNAs (lncRNAs) can act as molecular sponge or decoys for an RNA-binding protein (RBP) through their RBP-binding sites, thereby modulating the expression of all target genes of the corresponding RBP of ...
Kanser gen öncelleştirimi ve modül çıkarımına yönelik özgün yaklaşımlar
(Antalya Bilim Üniversitesi, 2019)