• English
    • Türkçe
  • English 
    • English
    • Türkçe
  • Login
View Item 
  •   DSpace Home
  • Akademik Arşiv / Institutional Repository
  • Mühendislik Fakültesi / Faculty of Engineering
  • Bilgisayar Mühendisliği Bölümü / Department of Computer Engineering
  • View Item
  •   DSpace Home
  • Akademik Arşiv / Institutional Repository
  • Mühendislik Fakültesi / Faculty of Engineering
  • Bilgisayar Mühendisliği Bölümü / Department of Computer Engineering
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

RBPmotif: a web server for the discovery of sequence and structure preferences of RNA-binding proteins

Thumbnail
View/Open
RBPmotif: a web server for the discovery of sequence and structure preferences of RNA-binding proteins (1.506Mb)
Date
2013
Author
Kazan, Hilal
Morris, Quaid
Metadata
Show full item record
Abstract
RBPmotif web server (http://www.rnamotif.org) implements tools to identify binding preferences of RNA-binding proteins (RBPs). Given a set of sequences that are known to be bound and unbound by the RBP of interest, RBPmotif provides two types of analysis: (i) de novo motif finding when there is no a priori knowledge on RBP’s binding preferences and (ii) analysis of structure preferences when there is a previously identified sequence motif for the RBP. De novo motif finding is performed with the previously published RNAcontext algorithm that learns discriminative motif models to identify both sequence and structure preferences. The results of this analysis include the inferred binding preferences of the RBP and the added predictive value of incorporating structure preferences. Second type of analysis investigates whether the instances of the previously identified sequence motif are enriched in a particular structure context in bound sequences, relative to its instances in unbound sequences. On completion, the results page shows the comparison of structure contexts of the motif instances between bound and unbound sequences and an assessment of statistical significance of detected preferences. In summary, RBPmotif web server enables the concurrent analysis of sequence and structure preferences of RBPs through a user-friendly interface.
URI
http://hdl.handle.net/20.500.12566/169
Collections
  • Bilgisayar Mühendisliği Bölümü / Department of Computer Engineering
  • PubMed İndeksli Yayınlar Koleksiyonu
  • Scopus İndeksli Yayınlar Koleksiyonu
  • WOS İndeksli Yayınlar Koleksiyonu

DSpace software copyright © 2002-2016  DuraSpace
Contact Us | Send Feedback
Theme by 
Atmire NV
 

 




sherpa/romeo


Browse

All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsTypeABU AuthorWOSScopusPubMedTRDizinErişimThis CollectionBy Issue DateAuthorsTitlesSubjectsTypeABU AuthorWOSScopusPubMedTRDizinErişim

My Account

LoginRegister

DSpace software copyright © 2002-2016  DuraSpace
Contact Us | Send Feedback
Theme by 
Atmire NV
 

 


|| Library || Antalya Bilim Üniversitesi || OAI-PMH ||

Antalya Bilim Üniversitesi Kütüphane ve Dokümantasyon Müdürlüğü, Antalya, Turkey
İçerikte herhangi bir hata görürseniz, lütfen bildiriniz: acikerisim@antalya.edu.tr

DSpace Repository:


DSpace 6.4-SNAPSHOT

Gemini Bilgi Teknolojileri A.Ş tarafından destek verilmektedir.