Başlık için Bilgisayar Mühendisliği Bölümü / Department of Computer Engineering listeleme

Toplam kayıt 35, listelenen: 30-35

    • SCITUNA: a network alignment approach for integrating multiple single-cell RNA-Seq datasets 

      Doğan, Onur; Erten, Burak Onur; Erten, Cesim; Houdjedj, Aissa; Kazan, Hilal; Krichen, Mohamed; Marouf, Yacine (15th International Symposium on Health Informatics and Bioinformatics, 2022)
      The throughput and cost of single-cell RNA sequencing (scRNA-seq) are in continuous improvement, and so is the demand for larger-scale scRNA-seq data, which could require integrating multiple datasets from different ...

    • Sex-biased expression of neuroimmune guidance cues in cardiovascular diseases 

      Marouf, Yacine; Doğan, Onur S.; Benavente, Ernest Diez; Pasterkamp, Gerard; den Ruijter, Hester M.; van Gils, Janine; Rayner, Katey; Kazan, Hilal (15th International Symposium on Health Informatics and Bioinformatics, 2022)
      Atherosclerotic vascular disease continues to be a leader of morbidity and mortality. Although sex hormones are known to play a role in this lipid- and inflammatory-driven disease, the underlying mechanisms are largely ...

    • Sparse data embedding and prediction by tropical matrix factorization 

      Omanović, Amra; Kazan, Hilal; Oblak, Polona; Curk, Tomaž (BMC Bioinformatics, 2021)
      Background Matrix factorization methods are linear models, with limited capability to model complex relations. In our work, we use tropical semiring to introduce non-linearity into matrix factorization models. We propose ...

    • Structure of conflict graphs in constraint alignment problems and algorithms 

      Alkan, Ferhat; Bıyıkoğlu, Türker; Demange, Marc; Erten, Cesim (Discrete Mathematics Theoretical Computer Science, 2019)
      We consider the constrained graph alignment problem which has applications in biological network analysis. Given two input graphs G1 = (V1, E1), G2 = (V2, E2), two vertices u1, v1 of G1 paired respectively to two vertices ...

    • Target-independent prediction of drug synergies using only drug lipophilicity 

      Kazan, Hilal; Yılancıoğlu, Kaan; Weinstein, Zohar B.; Meydan, Cem; Akhmetov, Azat; Toprak, Işıl; Durmaz, Arda; Iossifov, Ivan; Roth, Frederick P.; Çokol, Murat (Journal of Chemical Information and Modeling, 2014)
      Physicochemical properties of compounds have been instrumental in selecting lead compounds with increased drug-likeness. However, the relationship between physicochemical properties of constituent drugs and the tendency ...

    • A translational repression complex in developing mammalian neural stem cells that regulates neuronal specification 

      Zahr, Siraj K.; Yang, Guang; Kazan, Hilal; Borrett, Michael J.; Voronova, Anastassia; Kaplan, David R.; Miller, Freda D. (Neuron, 2018)
      The mechanisms instructing genesis of neuronal sub-types from mammalian neural precursors are not well understood. To address this issue, we have characterized the transcriptional landscape of radial glial precursors (RPs) ...