Yazar "Kaplan, David R." için listeleme
-
The P-body protein 4E-T represses translation to regulate the balance between cell genesis and establishment of the postnatal NSC pool
Kolaj, Adelaida; Zahr, Siraj K.; Wang, Beatrix S.; Krawec, Taylor; Kazan, Hilal; Yang, Guang; Kaplan, David R.; Miller, Freda D. (Elsevier, 2023)Here, we ask how developing precursors maintain the balance between cell genesis for tissue growth and establishment of adult stem cell pools, focusing on postnatal forebrain neural precursor cells (NPCs). We show that ... -
A translational repression complex in developing mammalian neural stem cells that regulates neuronal specification
Zahr, Siraj K.; Yang, Guang; Kazan, Hilal; Borrett, Michael J.; Voronova, Anastassia; Kaplan, David R.; Miller, Freda D. (Neuron, 2018)The mechanisms instructing genesis of neuronal sub-types from mammalian neural precursors are not well understood. To address this issue, we have characterized the transcriptional landscape of radial glial precursors (RPs) ...