Yazar "Houdjedj, Aissa" için listeleme
-
Identification and prioritization of personalized cancer drivers
Erten, Cesim; Houdjedj, Aissa; Kazan, Hilal; Taleb, Ahmed Amine (German Conference on Bioinformatics, 2022) -
A network-centric framework for the evaluation of mutual exclusivity tests on cancer drivers
Ahmed, Rafsan; Erten, Cesim; Houdjedj, Aissa; Kazan, Hilal; Yalcin, Cansu (Frontiers in Genetics, 2021)One of the key concepts employed in cancer driver gene identification is that of mutual exclusivity (ME); a driver mutation is less likely to occur in case of an earlier mutation that has common functionality in the same ... -
PersonaDrive: a method for the identification and prioritization of personalized cancer drivers
Erten, Cesim; Houdjedj, Aissa; Kazan, Hilal; Taleb Bahmed, Ahmed Amine (Bioinformatics, 2022)Motivation: A major challenge in cancer genomics is to distinguish the driver mutations that are causally linked to cancer from passenger mutations that do not contribute to cancer development. The majority of existing ... -
Ranking cancer drivers via betweenness-based outlier detection and random walks
Houdjedj, Aissa (Antalya Bilim Üniversitesi Lisansüstü Eğitim Enstitüsü, 2021)Recent cancer genomic studies have generated detailed molecular data on a large number of cancer patients. A key remaining problem in cancer genomics is the identification of driver genes. We propose BetweenNet, a ... -
Ranking cancer drivers via betweenness-based outlier detection and random walks
Erten, Cesim; Houdjedj, Aissa; Kazan, Hilal (BMC Bioinformatics, 2021)Background Recent cancer genomic studies have generated detailed molecular data on a large number of cancer patients. A key remaining problem in cancer genomics is the identification of driver genes. Results We propose ... -
RBPSponge: genome-wide identification of lncRNAs that sponge RBPs
HafezQorani, Saber; Houdjedj, Aissa; Arıcı, Mehmet; Said, Abdesselam; Kazan, Hilal (Bioinformatics, 2019)Long non-coding RNAs (lncRNAs) can act as molecular sponge or decoys for an RNA-binding protein (RBP) through their RBP-binding sites, thereby modulating the expression of all target genes of the corresponding RBP of ... -
SCITUNA: a network alignment approach for integrating multiple single-cell RNA-Seq datasets
Doğan, Onur; Erten, Burak Onur; Erten, Cesim; Houdjedj, Aissa; Kazan, Hilal; Krichen, Mohamed; Marouf, Yacine (15th International Symposium on Health Informatics and Bioinformatics, 2022)The throughput and cost of single-cell RNA sequencing (scRNA-seq) are in continuous improvement, and so is the demand for larger-scale scRNA-seq data, which could require integrating multiple datasets from different ...