Browsing by Author "Ahmed, Rafsan"
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MEXCOwalk: mutual exclusion and coverage based random walk to identify cancer modules
Ahmed, Rafsan; Baali, Ilyes; Erten, Cesim; Hoxha, Evis; Kazan, Hilal (Bioinformatics, 2019)Motivation: Genomic analyses from large cancer cohorts have revealed the mutational heterogeneity problem which hinders the identification of driver genes based only on mutation profiles. One way to tackle this problem ... -
A network-centric framework for the evaluation of mutual exclusivity tests on cancer drivers
Ahmed, Rafsan; Erten, Cesim; Houdjedj, Aissa; Kazan, Hilal; Yalcin, Cansu (Frontiers in Genetics, 2021)One of the key concepts employed in cancer driver gene identification is that of mutual exclusivity (ME); a driver mutation is less likely to occur in case of an earlier mutation that has common functionality in the same ... -
Utilizing mutual exclusivity for the identification of cancer driver gene modules
Ahmed, Rafsan (Antalya Bilim Üniversitesi Lisansüstü Eğitim Enstitüsü, 2020)Genomic analyses from large cancer cohorts have revealed the mutational heterogeneity problem which hinders the identification of driver genes based only on mutation profiles. One way to tackle this problem is to incorporate ...